Dementia Related Post

Fixed-Dose Reduction is not good!

I started coming off Pregabalin at the beginning of September last year. It has been a very long four months! 

With each reduction, I go through a week of hell! My head is all over the place! My mind will not stop, it hurts, and even my Tinnitus peeks to hammer home Pregablin’s attempt to force me to retake it! My epilepsy and Meniere’s is affected in a bad way. I can’t eat and keep it down, and sleeping is just impossible!

The strange thing is, the further I go down the road of coming off it, the harder those first weeks are becoming, and this seems to spill over longer into the following weeks.

I have a theory of why this should be.

The amount I reduce Pregabalin is the same each month. This is why I think my withdrawal symptoms are getting worse each month. 

As I go through each month, my body, and brain, are forced to accept the new lower dose, and the symptoms settle. However, the amount I reduce each month is the same, which means it is a more significant percentage of what my body is used to and therefore, the problems I have each month get worse. 

I know this doesn’t sound that easy to get your head around, so I’ll try to explain.

1st month:   medication 100%

Reduction. 25%

So I’ve reduced my medication by a quarter. 

2nd month: new medication 100%

This is now only 75% of what it was last month 

Reduction. stays the same 25%

Affectively my medication is reduced by a third this month…. 

3rd month: new medication 100%

This is now only 50% of what I was taking at the start. 

Reduction stays the same at 25%

Affectively my medication is reduced by half. 

4th month: new medication 100%

This is now only 25% of what I was initially on.

Reduction stays the same at 25%

This time I will be coming off the total amount. 

If someone is trying to beat their addiction or dependency, as in my case, the reduction dose should be reduced each month and not be a fixed amount. This will mean that it will take longer to beat the dependency. However, I think it would help with the increasing withdrawal problems of a fixed dose each time and ensure that you stay clear or clean. 

My fixed-dose reduction seems to leave me still craving the drug I’ve come off and takes a long time to be beaten finally, and I mean years! 

This process is the reverse of addiction, or dependency, where each month just a little more soothes the beast, but this increase only leads to death!

Next month is my last reduction, and I’m dreading the thought of it. I know what’s coming! 

2 replies »


  1. A really interesting read. I’m so proud of your achievements so far. I know it’s not been easy, but I’m convinced that you will reach your goal.
    Well done Dad 👍
    Love you C x💜


  2. Wow! I see what you mean! You just assume that the the reduction stays the same but as you’ve explained it reduces at a much quicker rate and bigger amounts 🤭 do the doctors not do the maths on this?! Then they wonder why people fail to beat their addictions. You have done incredibly well so far…. Keep going! You can do this! 💪🏼

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